Altamira Therapeutics Announces Significant Enhancement of Immune Checkpoint Inhibition Therapy in Combination with Zbtb46 mRNA Delivered with SemaPhore Nanoparticles in Animal Tumor Models

Hamilton, Bermuda, Aug. 12, 2024 (GLOBE NEWSWIRE) --

Altamira Therapeutics Ltd. (“Altamira” or the “Company”) (Nasdaq:CYTO), a company dedicated to developing and commercializing RNA delivery technology for targets beyond the liver, today announced the publication of a peer-reviewed article in Nature Immunology highlighting the important role of the Zbtb46 gene in the control of tumor growth and demonstrating a significant reduction in tumor growth in vivo through treatment with Zbtb46 mRNA delivered with Altamira’s SemaPhore™ nanoparticle technology.¹ The treatment effect was potentiated when combined with anti-PD1 immune checkpoint inhibition, inducing long-term remission and promoting immunological memory. The research was conducted by a group around Professor Kyunghee Choi of the Pathology & Immunology Department of Washington University School of Medicine (St. Louis, MO).